Al Qaeda commander Ayman al-Zawahiri issued an audio message on Sunday telling his supporters to prepare for a guerilla campaign in Syria against Assad, the West, and Iran, Reuters reports.

In the undated message, Zawahiri advises his fighters to remain patient and focus on a protracted conflict in Iraq and Syria. The message comes as Syrian dictator Bashar al Assad continues to consolidate gains on the battlefield with the support of Russia and Iran.

The message continued by saying Sunni jihadists have been targeted for their efforts to spread the Islamic “wave” and they should be prepared to fight the crusaders and their allies, the Shi’ites and Alawites. At this time, Al Qaeda does not officially claim ownership of any faction fighting Assad or the Islamic State. But with the continuously changing landscape on the battlefield, which groups still claim loyalty or report to Al-Qaeda, if any?

Al Qaeda has been present throughout the Syrian Civil War through its Syrian branch formally known as Jabhat al-Nusra. Perhaps as an indicator of the tumultuous nature of the war, allegiances and alliances within the jihadist groups in Syria have shifted periodically, and Nusra was no exception. After Abu Bakr al-Baghdadi announced that Jabhet al-Nusra was being absorbed by the newly emerging Islamic State in Iraq (a precursor to ISIS) in 2013, Nusra leader Abu Mohammed al-Julani rejected the claim and insisted allegiance to Al Qaeda.