Police said a truck bomb exploded outside the Safari Hotel at the K5 intersection, which is lined with government offices, restaurants and kiosks, flattening buildings and setting vehicles on fire. A separate blast struck the Medina district two hours later.
Abshir Abdi Ahmed said the toll comes from doctors at hospitals he has visited in Mogadishu. Many of the bodies in hospital mortuaries have not yet been identified, he said.
It is the single deadliest attack ever in the Horn of Africa nation.